Zika Virus Net is the web resource for anyone interested in Zika virus. Zika virus (ZIKV) is an insect-borne virus, of the flavivirus genus, that is spread by Aedes mosquitoes. The most common symptoms of Zika virus disease (Zika) are fever, rash, joint pain, and red eye. The illness is usually mild with symptoms lasting from several days to a week. Severe disease requiring hospitalization is uncommon. The symptoms of Zika are similar to those of dengue and chikungunya, which are diseases caused by other viruses spread by the same type of mosquitoes. Zika virus can be spread from a pregnant woman to her unborn baby. There have been reports of a serious birth defect of the brain called microcephaly and other poor pregnancy outcomes in babies of mothers who were infected with Zika virus while pregnant. On February 1st, 2016, the WHO declared the Zika outbreak as a Public Health Emergency of International Concern (PHEIC). As of August 2017 the number of new Zika virus cases in the Americas had fallen dramatically.

The objectives of Zika Virus Net are to be the public and professional information resource for zika fever and to serve as a network in the exchange of information and news related to zika.

• Zika Infections Escalating in 2023 — Precision Vaccinations News - Precision Vaccinations
  Sun, 03 Sep 2023 07:00 GMT
• Researchers discover how Zika virus persists in the placenta - News-Medical.Net
  Tue, 26 Sep 2023 20:45 GMT
• Refocusing on Zika virus in Brazil - The Lancet
  Sat, 23 Sep 2023 07:00 GMT
• How siRNA Protects Mosquitoes from Viral Infections Like Zika and ... - Genetic Engineering & Biotechnology News
  Mon, 25 Sep 2023 09:50 GMT
• Mosquitoes capable of transmitting Zika virus detected in Grand Rapids - MLive.com
  Thu, 07 Sep 2023 07:00 GMT
• Cambodia reports 1st Zika virus case since 2016 - Outbreak News ... - Outbreak News Today
  Sun, 24 Sep 2023 20:40 GMT
• Zika Virus Therapeutics Market: A Glimpse into 2031 Trends and Key Players - Benzinga
  Tue, 26 Sep 2023 06:41 GMT
• Kingdom confirms first case of Zika infection in seven years - The Star Online
  Tue, 26 Sep 2023 00:14 GMT
• 2023-2030 Zika Virus Therapeutics Market is Growing Rapidly with Emerging Pattern - Benzinga
  Tue, 26 Sep 2023 11:47 GMT
• Second Zika virus case reported in City - Hindustan Times
  Wed, 06 Sep 2023 07:00 GMT
• Dengue and Zika mosquito detected in Lisbon - The Portugal News
  Thu, 28 Sep 2023 16:05 GMT
• Central team in Kolhapur to study Zika case - ETHealthWorld
  Sat, 09 Sep 2023 07:00 GMT
• Disease-carrying mosquitoes moving north - The Daily Telegram
  Sun, 01 Oct 2023 08:01 GMT
• BMC intensifies aedes mosquitoes detection programme, finds 900 spots a day - Hindustan Times
  Sun, 01 Oct 2023 17:31 GMT
• Genetically modified mosquitoes and vaccines -- what you need to know about dengue fever - ABC News
  Thu, 28 Sep 2023 07:00 GMT

• PRO/AH/EDR> Invasive mosquito - France (03): (BT)
  Mon, 06 Sep 2021 21:28:53 -0400
  Yellow Fever, Zika virus, Dengue, Chikungunya -- France
  A potentially deadly mosquito that can carry viruses such as yellow fever and Zika has been spotted in Brittany, northern France, sparking fears they may soon land on British shores. Asian tiger mosquitoes [_Aedes albopictus_] have been confirmed to be in the commune of Domagne in the department of Ile-et-Vilaine in western Brittany.
  Health authorities are preparing an intensive campaign to rid the area of the insects with strong insecticides.
  The creatures were 1st seen in France in the

• HSPA13 modulates type I interferon antiviral pathway and NLRP3 inflammasome to restrict dengue virus infection in macrophages Sat, 30 Sep 2023 06:00:00 -0400
  Dengue virus (DENV) is a type of arthropod-borne Flavivirus, which leads to a series of serious diseases like dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). DENV has a devastating health and economic impact worldwide. However, there are no suitable drugs to combat the virus. Here we reported that HSPA13, also known as stress chaperone (STCH), is a member of the HSP70 family and is a key regulator of type I interferon (IFN-I) and pro-inflammatory responses during DENV infection....
• Metabolic response to CNS infection with flaviviruses Fri, 29 Sep 2023 06:00:00 -0400
  Flaviviruses are arthropod-borne RNA viruses found worldwide that, when introduced into the human body, cause diseases, including neuroinfections, that can lead to serious metabolic consequences and even death. Some of the diseases caused by flaviviruses occur continuously in certain regions, while others occur intermittently or sporadically, causing epidemics. Some of the most common flaviviruses are West Nile virus, dengue virus, tick-borne encephalitis virus, Zika virus and Japanese...
• The 3' terminal region of Zika virus RNA contains a conserved G-quadruplex and is unfolded by human DDX17 Fri, 29 Sep 2023 06:00:00 -0400
  Zika virus (ZIKV) infection remains a worldwide concern, and currently, no effective treatments or vaccines are available. Novel therapeutics are an avenue of interest that could probe viral RNA-human protein communication to stop viral replication. One specific RNA structure, G-quadruplexes (G4s), possess various roles in viruses and all domains of life, including transcription and translation regulation, genome stability, and serving as nucleation points for RNA liquid-liquid phase separation....
• Phylodynamics of dengue virus 2 in Nicaragua leading up to the 2019 epidemic reveals a role for lineage turnover Thu, 28 Sep 2023 06:00:00 -0400
  CONCLUSIONS: The timing of its emergence, along with a statistical signal of adaptive evolution and distinctive amino acid substitutions, the latest in the NS5 gene, suggest that this lineage may have increased fitness relative to the prior dominant DENV-2 strains. This may have contributed to the intensity of the 2019 DENV-2 epidemic, in addition to previously identified immunological factors associated with pre-existing Zika virus immunity.
• Better late than never: sleep still supports memory consolidation after prolonged periods of wakefulness Thu, 28 Sep 2023 06:00:00 -0400
  While the benefits of sleep for associative memory are well established, it is unclear whether single-item memories profit from overnight consolidation to the same extent. We addressed this question in a preregistered, online study and also investigated how the temporal proximity between learning and sleep influences overnight retention. Sleep relative to wakefulness improved retention of item and associative memories to similar extents irrespective of whether sleep occurred soon after learning...
• Multi-epitope Antigen for Specific Serological Detection of Dengue Viruses Thu, 28 Sep 2023 06:00:00 -0400
  Dengue is an infectious disease of global health concern that continues to require surveillance. Serological testing has been used to investigate dengue-infected patients, but specificity is affected by the co-circulation of ZIKA virus (ZIKV), which shares extensive antigen similarities. The goal of this study was the development of a specific dengue virus (DENV) IgG ELISA based on a multi-epitope NS1-based antigen for antibody detection. The multi-epitope protein (T-ΔNS1), derived from a...
• A Birth Cohort Follow-Up Study on Congenital Zika Virus Infection in Vietnam Thu, 28 Sep 2023 06:00:00 -0400
  We assessed the development, sensory status, and brain structure of children with congenital Zika virus (ZIKV) infection (CZI) at two years and preschool age. CZI was defined as either ZIKV RNA detection or positive ZIKV IgM and neutralization test in the cord or neonatal blood. Twelve children with CZI born in 2017-2018 in Vietnam, including one with Down syndrome, were assessed at 23-25.5 months of age, using Ages and Stages Questionnaire (ASQ-3), ASQ:Social-Emotional (ASQ:SE-2), Modified...
• Broad-Spectrum Antiviral Activity of Influenza A Defective Interfering Particles against Respiratory Syncytial, Yellow Fever, and Zika Virus Replication In Vitro Thu, 28 Sep 2023 06:00:00 -0400
  New broadly acting and readily available antiviral agents are needed to combat existing and emerging viruses. Defective interfering particles (DIPs) of influenza A virus (IAV) are regarded as promising options for the prevention and treatment of IAV infections. Interestingly, IAV DIPs also inhibit unrelated viral infections by stimulating antiviral innate immunity. Here, we tested the ability of IAV DIPs to suppress respiratory syncytial, yellow fever and Zika virus infections in vitro. In human...
• Low CCL2 and CXCL8 Production and High Prevalence of Allergies in Children with Microcephaly Due to Congenital Zika Syndrome Thu, 28 Sep 2023 06:00:00 -0400
  Congenital Zika Syndrome (CZS) is associated with an increased risk of microcephaly in affected children. This study investigated the peripheral dysregulation of immune mediators in children with microcephaly due to CZS. Gene expression quantified by qPCR in whole blood samples showed an increase in IFNγ and IL-13 transcripts in children affected with microcephaly compared to the control group. The microcephaly group exhibited significantly decreased CCL2 and CXCL8 levels in serum, quantified by...
• Arboviral Risk Associated with Solid Organ and Hematopoietic Stem Cell Grafts: The Prophylactic Answers Proposed by the French High Council of Public Health in a National Context Thu, 28 Sep 2023 06:00:00 -0400
  Diseases caused by arboviruses are on the increase worldwide. In addition to arthropod bites, most arboviruses can be transmitted via accessory routes. Products of human origin (labile blood products, solid organs, hematopoietic stem cells, tissues) present a risk of contamination for the recipient if the donation is made when the donor is viremic. Mainland France and its overseas territories are exposed to a complex array of imported and endemic arboviruses, which differ according to their...