Zika Virus Net is the web resource for anyone interested in Zika virus. Zika virus (ZIKV) is an insect-borne virus, of the flavivirus genus, that is spread by Aedes mosquitoes. The most common symptoms of Zika virus disease (Zika) are fever, rash, joint pain, and red eye. The illness is usually mild with symptoms lasting from several days to a week. Severe disease requiring hospitalization is uncommon. The symptoms of Zika are similar to those of dengue and chikungunya, which are diseases caused by other viruses spread by the same type of mosquitoes. Zika virus can be spread from a pregnant woman to her unborn baby. There have been reports of a serious birth defect of the brain called microcephaly and other poor pregnancy outcomes in babies of mothers who were infected with Zika virus while pregnant. On February 1st, 2016, the WHO declared the Zika outbreak as a Public Health Emergency of International Concern (PHEIC). As of August 2017 the number of new Zika virus cases in the Americas had fallen dramatically.

The objectives of Zika Virus Net are to be the public and professional information resource for zika fever and to serve as a network in the exchange of information and news related to zika.

• Study reveals the inevitability of Zika virus dumbbell-1 structure for viral pathogenesis - News-Medical.Net
  Thu, 26 Jan 2023 16:01 GMT
• Caribbean Countries Confront Zika Outbreaks in 2023 - Zika News
  Sat, 28 Jan 2023 17:57 GMT
• Caribbean Nations urged to stay alert for Dengue and Zika ... - Breaking Belize News
  Fri, 03 Feb 2023 19:14 GMT
• GeoVax Labs Shares Rise 9% After Zika Vaccine Patent Allowance Notice - MarketWatch
  Wed, 25 Jan 2023 16:28 GMT
• Promising efforts to develop an mRNA vaccine against Zika - The Lancet
  Thu, 19 Jan 2023 08:00 GMT
• 8 Viruses To Keep In Mind, According To WHO | HealthNews - Healthnews.com
  Wed, 01 Feb 2023 15:53 GMT
• Remarks by Vice President Harris on the Administration's Efforts to ... - The White House
  Fri, 03 Feb 2023 22:38 GMT
• The Last of Us: A Cordyceps Infection Is a Lot Closer Than You Think - Collider
  Tue, 31 Jan 2023 03:45 GMT
• Unusual Type of Antibody Shows Ultrapotent Activity Against Zika - Weill Cornell Medicine Newsroom
  Fri, 18 Nov 2022 08:00 GMT
• Zika: the unknown epidemic and PAHO’s swift response - Pan American Health Organization
  Fri, 28 Oct 2022 16:49 GMT
• Zika: Wisconsin Data - Wisconsin Department of Health Services
  Thu, 10 Nov 2022 08:00 GMT
• Zika Virus Facts and Statistics: What You Need to Know - Verywell Health
  Tue, 29 Nov 2022 08:00 GMT
• Researchers determine which animal kills people the most - Armenia News
  Sat, 04 Feb 2023 05:42 GMT
• » How human cells become Zika virus factories - La Jolla Institute for Immunology
  Mon, 12 Sep 2022 07:00 GMT
• The Forgotten Virus: Zika Families and Researchers Struggle for Support - The New York Times
  Tue, 16 Aug 2022 07:00 GMT

• PRO/AH/EDR> Invasive mosquito - France (03): (BT)
  Mon, 06 Sep 2021 21:28:53 -0400
  Yellow Fever, Zika virus, Dengue, Chikungunya -- France
  A potentially deadly mosquito that can carry viruses such as yellow fever and Zika has been spotted in Brittany, northern France, sparking fears they may soon land on British shores. Asian tiger mosquitoes [_Aedes albopictus_] have been confirmed to be in the commune of Domagne in the department of Ile-et-Vilaine in western Brittany.
  Health authorities are preparing an intensive campaign to rid the area of the insects with strong insecticides.
  The creatures were 1st seen in France in the

• Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement Fri, 03 Feb 2023 06:00:00 -0500
  Mosquito-borne flaviviruses including Zika virus (ZIKV) represent a public health problem in some parts of the world. Although ZIKV infection is predominantly asymptomatic or associated with mild symptoms, it can lead to neurological complications. ZIKV infection can also cause antibody-dependent enhancement (ADE) of infection with similar viruses, warranting further studies of virion assembly and the function of envelope (E) protein-specific antibodies. Although extracellular vesicles (EVs)...
• Quantifying heterogeneities in arbovirus transmission: Description of the rationale and methodology for a prospective longitudinal study of dengue and Zika virus transmission in Iquitos, Peru (2014-2019) Thu, 02 Feb 2023 06:00:00 -0500
  Current knowledge of dengue virus (DENV) transmission provides only a partial understanding of a complex and dynamic system yielding a public health track record that has more failures than successes. An important part of the problem is that the foundation for contemporary interventions includes a series of longstanding, but untested, assumptions based on a relatively small portion of the human population; i.e., people who are convenient to study because they manifest clinically apparent...
• Identification of Novel Anti-ZIKV Drugs from Viral-Infection Temporal Gene Expression Profiles Mon, 30 Jan 2023 06:00:00 -0500
  Zika virus (ZIKV) infections are typically asymptomatic but cause severe neurological complications (e.g. Guillain-Barré syndrome in adults, and microcephaly in newborns). There are currently no specific therapy or vaccine options available to prevent ZIKV infections. Temporal gene expression profiles of ZIKV-infected human brain microvascular endothelial cells (HBMECs) were used in this study to identify genes essential for viral replication. These genes were then used to identify novel...
• Wolbachia wAlbB remains stable in Aedes aegypti over 15 years but exhibits genetic background-dependent variation in virus blocking Mon, 30 Jan 2023 06:00:00 -0500
  The ability of the maternally transmitted endosymbiotic bacterium Wolbachia to induce cytoplasmic incompatibility (CI) and virus blocking makes it a promising weapon for combatting mosquito-borne diseases through either suppression or replacement of wild-type populations. Recent field trials show that both approaches significantly reduce the incidence of dengue fever in humans. However, new questions emerge about how Wolbachia-mosquito associations will co-evolve over time and whether...
• Risk of adverse outcomes in offspring with RT-PCR confirmed prenatal Zika virus exposure: An individual participant data meta-analysis of 13 cohorts in the Zika Brazilian Cohorts Consortium Mon, 30 Jan 2023 06:00:00 -0500
  BACKGROUND: Knowledge regarding the risks associated with Zika virus (ZIKV) infections in pregnancy has relied on individual studies with relatively small sample sizes and variable risk estimates of adverse outcomes, or on surveillance or routinely collected data. Using data from the Zika Brazilian Cohorts Consortium, this study aims, to estimate the risk of adverse outcomes among offspring of women with RT-PCR-confirmed ZIKV infection during pregnancy and to explore heterogeneity between...
• RIG-I and MDA5 are modulated by bone morphogenetic protein (BMP6) and are essential for restricting Zika virus infection in human Sertoli cells Mon, 30 Jan 2023 06:00:00 -0500
  Sexual transmission of Zika virus (ZIKV) is associated with virus persistence in the testes and shedding in the seminal fluid for months after recovery. We previously demonstrated that ZIKV can establish long-term replication without causing cytotoxicity in human Sertoli cells (SC), responsible for maintaining the immune privileged compartment of seminiferous tubules. Functional gene expression analyses also predicted activation of multiple virus sensing pathways including TLR3, RIG-I, and MDA5....
• Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses Mon, 30 Jan 2023 06:00:00 -0500
  RNA viruses continue to remain a clear and present threat for potential pandemics due to their rapid evolution. To mitigate their impact, we urgently require antiviral agents that can inhibit multiple families of disease-causing viruses, such as arthropod-borne and respiratory pathogens. Potentiating host antiviral pathways can prevent or limit viral infections before escalating into a major outbreak. Therefore, it is critical to identify broad-spectrum antiviral agents. We have tested a small...
• Infections in travellers returning to the UK: a retrospective analysis (2015-2020) Sat, 28 Jan 2023 06:00:00 -0500
  CONCLUSIONS: None of the top five infections diagnosed by RIPL in travellers are vaccine-preventable, therefore understanding traveller demographics, destination-specific risk factors and encouraging preventative behaviours is the best available strategy to reduce the number of returning travellers who become infected. Prompt referral of acute samples with a detailed travel history, including purpose of travel and activities undertaken as well as dates and destinations can be a valuable tool in...
• RSAD2: An exclusive target protein for Zika virus comparative modeling, characterization, energy minimization and stabilization Fri, 27 Jan 2023 06:00:00 -0500
  CONCLUSION: A large amount of sequence and structural data is now available, for tertiary protein structure prediction, hence implying a computational approach in all the aspects becomes an opportunistic strategy. The best three-dimensional structure of RSAD2 was built and was confirmed with energy minimization, secondary structure validation and torsional angles stabilization. This modeled protein is predicted to play a role in the development of drugs against Zika virus infection.
• Seasonal changes in the diversity, host preferences and infectivity of mosquitoes in two arbovirus-endemic regions of Costa Rica Thu, 26 Jan 2023 06:00:00 -0500
  CONCLUSION: Seasonal patterns in mosquito community dynamics in coastal areas of Costa Rica have strong differences despite a geographical proximity. The NDVI influences mosquito diversity at the regional scale more than at the local scale. However, year-long continuous sampling is required to better understand local dynamics.