New and Updated Clinical Zika Virus Vaccine Trials
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Evaluation of Two Zika Viruses for Use in Controlled Human Infection Models (CHIM)
Nov 17, 2021 | 18:00 pmCondition: Zika VirusInterventions: Other: ZIKV-SJRP/2016-184 Strain; Other: Experimental: ZIKV-Nicaragua/2016 Strain; Biological: PlaceboSponsor: National Institute of Allergy and Infectious Diseases (NIAID)Recruiting
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Adherence to Care for Children With Congenital Zika Virus Infection in Puerto Rico
Sep 13, 2021 | 18:00 pmConditions: Zika Virus Infection; Adherence, PatientIntervention: Behavioral: Community Health WorkerSponsors: University of Puerto Rico; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Massachusetts General HospitalRecruiting
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A Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas
Jun 8, 2021 | 18:00 pmCondition: Zika VirusInterventions: Biological: mRNA-1893; Biological: PlaceboSponsor: ModernaTX, Inc.Active, not recruiting
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Research Study to Assess New Chikungunya and Zika Vaccines in Healthy Adults in Mexico.
Jun 22, 2020 | 18:00 pmConditions: Chikungunya; ZikaInterventions: Biological: CHIK low dose; Biological: CHIK mid dose; Biological: CHIK high dose; Biological: ZIKA low dose; Biological: ZIKA mid dose; Biological: ZIKA high dose; Biological: Saline placeboSponsor: University of OxfordCompleted
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Evaluation of Medical Conditions Associated With Zika Virus Infection in Managua, Nicaragua
Dec 2, 2019 | 18:00 pmCondition: Zika VirusIntervention: Sponsors: RTI International; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); University of North Carolina, Chapel Hill; Sustainable Sciences Institute (Managua, Nicaragua); Ministry of Health NicaraguaUnknown status
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Safety, Tolerability, and Immunogenicity of Zika Vaccine mRNA-1893 in Healthy Flavivirus Seropositive and Seronegative Adults
Aug 22, 2019 | 18:00 pmCondition: Zika VirusInterventions: Biological: mRNA-1893; Other: PlaceboSponsors: ModernaTX, Inc.; Biomedical Advanced Research and Development AuthorityCompleted
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Safety and Immunogenicity of a Novel Vaccine Formulation MV-ZIKA-RSP (V187-001)
Jul 25, 2019 | 18:00 pmCondition: Zika Virus InfectionInterventions: Biological: Two MV-ZIKA-RSP vaccinations (high dose); Biological: Two MV-ZIKA-RSP vaccination (low dose); Biological: One MV-ZIKA-RSP vaccination (high dose) and one placebo; Other: Two placebo injectionSponsor: Themis Bioscience GmbHCompleted
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Safety and Immunogenicity of a Candidate ZIKV Vaccine (ZIKA001)
Jul 11, 2019 | 18:00 pmCondition: ZikaIntervention: Biological: ChAdOx1 ZikaSponsor: University of OxfordCompleted
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Sensorimotor Outcomes of Children Exposed to Foetal Zika Virus Infection
Sep 20, 2018 | 18:00 pmCondition: Zika Virus InfectionInterventions: Behavioral: First trimester; Behavioral: Second trimesterSponsor: University of Sao PauloCompleted
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Study in Healthy Volunteers Evaluating Safety and Pharmacokinetics of Zika Virus Immune Globulin (ZIKV-IG)
Aug 10, 2018 | 18:00 pmConditions: Zika Virus Infection; Zika Virus DiseaseInterventions: Biological: Zika Virus Immune Globulin (ZIKV-IG); Other: PlaceboSponsor: Emergent BioSolutionsCompleted
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Vertical Exposure to Zika Virus and Its Consequences for Child Neurodevelopment (ZIKVIRUSIFF)
Aug 21, 2017 | 18:00 pmConditions: ZIKA VIRUS INFECTION; Child Development; MicrocephalyIntervention: Other: Child exposed Zika virus provedSponsors: Oswaldo Cruz Foundation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Rio de Janeiro State Research Supporting Foundation (FAPERJ)Unknown status
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Dermatologic Manifestations of Zika Virus
Jul 25, 2017 | 18:00 pmCondition: Zika Virus Symptoms and the Associated ExanthemaIntervention: Other: SurveySponsors: Northwestern University; Pontificia Universidad Catolica Madre y MaestraWithdrawn
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Zika Case Definition and Surveillance Study
May 18, 2017 | 18:00 pmCondition: Zika Virus DiseaseIntervention: Sponsor: Sanofi Pasteur, a Sanofi CompanyCompleted
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Study on the Persistence of Zika Virus (ZIKV) in Body Fluids of Patients With ZIKV Infection in Brazil
Apr 10, 2017 | 18:00 pmCondition: Zika VirusIntervention: Diagnostic Test: RT-PCRSponsors: Oswaldo Cruz Foundation; World Health Organization; Ministry of Health, Brazil; Walter Reed Army Institute of Research (WRAIR); Wellcome Trust; National Institute of Allergy and Infectious Diseases (NIAID)Completed
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Phase I, Randomized, Double-blinded, Placebo-Controlled Dose De-escalation Study to Evaluate Safety and Immunogenicity of Alum Adjuvanted Zika Virus Purified Inactivated Vaccine (ZPIV) in Adults in a Flavivirus Endemic Area
Jan 2, 2017 | 18:00 pmCondition: Zika Virus InfectionInterventions: Other: Placebo; Biological: Zika Virus Purified Inactivated Vaccine (ZPIV)Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)Completed
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Zika-Vaccine Dose Finding Study Regarding Safety, Immunogenicity and Tolerability (V186-001)
Dec 19, 2016 | 18:00 pmCondition: Zika VirusInterventions: Biological: MV-ZIKA; Other: PlaceboSponsor: Themis Bioscience GmbHCompleted
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Understanding Excretion and Infectivity of Zika Virus in Semen During and After Infection
Dec 2, 2016 | 18:00 pmCondition: Zika VirusIntervention: Other: Semen analysis and semen PCR for Zika virusSponsors: Trinidad and Tobago IVF and Fertility Centre; Institute of Tropical Medicine, BelgiumCompleted
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Zika Virus Purified Inactivated Vaccine (ZPIV) Accelerated Vaccination Schedule Study
Oct 18, 2016 | 18:00 pmCondition: ZikaInterventions: Biological: Zika Virus Purified Inactivated Vaccine; Other: PlaceboSponsors: Kathryn Stephenson; Walter Reed Army Institute of Research (WRAIR); National Institute of Allergy and Infectious Diseases (NIAID)Completed
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Zika Virus Infection's Pregnancy Consequences in French Department of America
Sep 27, 2016 | 18:00 pmCondition: Incidence of ZIKV Infection on Fetus During the PregnancyIntervention: Sponsor: Institut National de la Santé Et de la Recherche Médicale, FranceCompleted
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Zika Virus Infection's Neonatal and Pediatric Consequences in French Department of America
Jun 22, 2016 | 18:00 pmCondition: Zika Virus Infection on Fetus and Child During the PregnancyInterventions: Other: fundus examination; Other: Head ultrasoundSponsor: Institut National de la Santé Et de la Recherche Médicale, FranceUnknown status
